2,N,N-Trimethyltryptamine, 2,N,N-TMT, or 2-Me-DMT is a tryptamine derivative that is a psychedelic drug. It was invented by Alexander Shulgin and reported in his book TiHKAL (#34). It is claimed to show psychoactive effects at a dosage of 50–100 mg orally, but these are relatively mild compared to other similar drugs, suggesting that while the 2-methyl group has blocked the binding of metabolic enzymes, it is also interfering with binding to the 5HT2A receptor target that mediates the hallucinogenic effects of these drugs.
IUPAC name: (2-(2-methyl-1H-indol-3-yl)-1-methyl-ethyl)dimethylamine
Other name: 2,N,N-trimethyltryptamine, 2,N,N-TMT
The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications