Buy 4-Methylaminorex Crystals for Advanced Neuropharmacological Research

4-Methylaminorex (4-MAR, 4-MAX) is a high-purity research compound belonging to the 2-amino-5-aryloxazoline class of synthetic stimulants[reference:0][reference:1]. First synthesized in 1960 by McNeil Laboratories[reference:2][reference:3], this compound has garnered significant interest in neuropharmacological research due to its potent central nervous system stimulant properties and unique monoaminergic activity profile[reference:4]. Our research-grade crystals are manufactured under strict laboratory conditions, ensuring a purity level of ≥99% as verified by HPLC and GC/MS testing. Researchers across Europe trust this compound for consistent, reproducible results in their experimental work. For detailed chemical background, refer to the PubChem database for comprehensive compound information[reference:5].

Product Overview

This synthetic compound features a 2-amino-5-aryloxazoline core structure with a methyl group at the 4-position of the oxazoline ring. The compound is structurally characterized by the molecular formula C₁₀H₁₂N₂O and a molecular weight of 176.21 g/mol[reference:6][reference:7]. Pharmacologically, it acts as a potent norepinephrine-dopamine releasing agent, producing effects comparable to methamphetamine but with a significantly longer duration of action[reference:8][reference:9].

In animal studies, this compound stimulates spontaneous activity in mice and produces sympathomimetic effects in dogs[reference:10]. In discrimination studies, it generalizes to d-amphetamine, with a potency approximately half that of d-amphetamine[reference:11]. The compound exhibits potent reinforcing activity in self-administration studies, with rates comparable to cocaine[reference:12]. The foundational chemistry of such compounds is well-documented in resources like Wikipedia’s entry on 4-methylaminorex, providing useful context for researchers[reference:13].

This research chemical is supplied as fine crystalline powder, ideal for in vitro transporter binding assays, in vivo behavioral studies, and receptor interaction experiments. The material is not intended for human consumption but serves as a valuable tool for academic and industrial research laboratories across Europe.

Key Specifications

For reference standards and analytical validation protocols, researchers often consult the Sigma-Aldrich technical library for validated methodologies.

Research Applications

This compound is primarily utilized in the following research areas:

• Neuropharmacology: Investigating norepinephrine and dopamine transporter interactions. Studies demonstrate that 4-methylaminorex acts as a potent releasing agent for these monoamines, producing sustained elevations in synaptic neurotransmitter levels[reference:18].
• Behavioral Studies: Assessing psychostimulant effects, locomotor activity, and reinforcing properties in animal models. The compound has been shown to produce potent reinforcing activity in rhesus monkeys at rates comparable to cocaine[reference:19].
• Receptor Binding Assays: Evaluating affinity for monoamine transporters and studying structure-activity relationships of 2-amino-5-aryloxazoline derivatives[reference:20].
• Metabolic Profiling: Studying phase I metabolism pathways and pharmacokinetic properties, with an elimination half-life of 10-19 hours[reference:21].

Researchers working with this crystalline material benefit from its stable form, which facilitates accurate weighing and dissolution for precise dosing protocols.

Quality & Purity

Our 4-methylaminorex crystals undergo rigorous quality control procedures to guarantee batch-to-batch consistency. Each batch is analyzed using:

1. High-Performance Liquid Chromatography (HPLC) – to determine purity ≥99% and identify organic impurities.
2. Gas Chromatography/Mass Spectrometry (GC/MS) – to confirm molecular identity and detect volatile impurities.
3. Nuclear Magnetic Resonance (NMR) – available on request for structural verification.

All certificates of analysis (CoA) are provided with every order, ensuring full transparency and traceability for your research documentation.

Storage & Handling

To maintain the integrity of this crystalline material, please adhere to the following guidelines:

• Store in a cool, dry environment (15–25°C) away from direct light.
• Keep container tightly sealed when not in use to prevent moisture absorption and degradation.
• Use appropriate personal protective equipment (PPE) during handling, including gloves and safety goggles.
• Dispose of unused material in accordance with local laboratory waste regulations.

Why Choose This Product

Selecting the right supplier for research compounds is critical to the success of your work. Here is why our product stands out:

• Verified Purity: Every batch is tested independently to confirm ≥99% purity using validated HPLC and GC/MS methods.
• Comprehensive Documentation: CoA, MSDS, and analytical reports included.
• European Distribution: Fast, discreet shipping from within the EU – no customs delays.
• Responsive Support: Our scientific team is available to answer technical queries.
• Competitive Pricing: Volume discounts available for bulk orders.

Frequently Asked Questions (FAQs)

What is 4-methylaminorex used for?

This compound is a research chemical used primarily in neuropharmacological studies to explore monoamine transporter interactions, psychostimulant mechanisms, and behavioral pharmacology. It is not for human or veterinary use.

How does 4-methylaminorex compare to amphetamine?

This compound produces effects comparable to methamphetamine but with a longer duration of action[reference:22]. Its potency is approximately half that of d-amphetamine, and it generalizes to d-amphetamine in discrimination studies[reference:23].

Is 4-methylaminorex legal to purchase in Europe?

Legality varies by country. It is the buyer’s responsibility to verify local regulations before ordering. Our product is supplied for legitimate research purposes only.

What purity level can I expect?

Our 4-methylaminorex crystals are consistently tested at ≥99% purity via HPLC and GC/MS. A certificate of analysis is provided with each shipment.

How should I store 4-methylaminorex crystals?

Store in a sealed container at room temperature, away from light and moisture. Proper storage ensures stability for up to 24 months.

Buy 4-methylaminorex crystals today and advance your research with confidence. Backed by rigorous quality assurance and fast EU delivery, our product is the preferred choice for discerning scientists.